AMD
Architecture
CDNA 2 powers the Instinct MI210 and MI250/MI250X accelerators. It introduced multi-die packaging with up to 128 GB HBM2e and Infinity Fabric for die-to-die communication.
AI Relevance
With up to 128 GB HBM2e memory and strong ROCm support, CDNA 2 GPUs can host large language models. The MI250X was used in the Frontier exascale supercomputer and supports major AI frameworks.
Agentic Coding
CThis model is still usable for agentic-coding, but it is not the most specialized pick. It belongs to a current frontier family for local AI. It should run, but memory headroom will be limited. Known channels: huggingface, ollama, lm-studio.
Chat
CThis model is a direct match for chat. It belongs to a current frontier family for local AI. It fits natively with comfortable headroom. Known channels: huggingface, ollama, lm-studio.
Coding
CThis model is a direct match for coding. It belongs to a current frontier family for local AI. It should run, but memory headroom will be limited. Known channels: huggingface, ollama, lm-studio.
RAG
CThis model is a direct match for rag. It sits in the middle of the current model mix. It fits natively with comfortable headroom. Known channels: huggingface, ollama, lm-studio.
Reasoning
CThis model is a direct match for reasoning. It belongs to a current frontier family for local AI. It fits natively with comfortable headroom. Known channels: huggingface, ollama, lm-studio.
Qwen3-Coder-Next
Qwen3.5 35B A3BQwen 2.5 Coder 32BQwen3-Coder 30B A3B InstructQwen3-VL 30B A3B InstructQwen3.5 27Bgemma 3 27b it
Devstral Small 2 24B Instruct
Llama 3.3 70BDevstral Small 1.1Qwen 2.5 72BQwen 2.5 VL 72BCodestral 2 25.08Qwen3.5 9BDeepSeek R1 0528 Qwen3 8BQwen3.5 4BQwen2.5 3B Instruct
gemma 2bQwen2.5 1.5B Instruct
DeepSeek R1 671BDevstral 2 123B Instruct
GLM-5
Kimi K2.5Mistral Large 3Mistral Small 4 119BQwen3-Coder 480B A35B InstructQwen3.5 122B A10BDeepSeek V3 671BMixtral 8x22BQwen 3 235B A22BQwen3.5 397B A17BLlama 4 Maverick 17B 128E
Command A 111BJust out of reach
High-quality models that need a bit more memory
Upgrade paths
See what you unlock with more powerful hardware
Upgrade options
NVIDIA A100 80GBNext step up~$15,000 MSRP
~$15,000 MSRP
~$8,000 MSRP
