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All estimates are approximations based on mathematical models and public specifications. Actual performance may vary. Do not make purchasing decisions based solely on these estimates.

Data sourced from Hugging Face, Ollama, and official model documentation. Model names and logos are trademarks of their respective owners.

© 2026 Will It Run AI — Fase Consulting Ibiza, S.L. (NIF: B57969656)

Home/Falcon 40B Instruct/on AMD Instinct MI210 64GB

Can it run?

Can AMD Instinct MI210 64GB run Falcon 40B Instruct?

CUsable

Runs well

Using Q5_K_M in Ollama

Capabilities:

Fit status

Runs well

Decode

39.4 tok/s

TTFT

4908 ms

Safe context

8K

Memory

42.7 GB / 64.0 GB

Memory breakdown

Weights28.8 GB
KV Cache6.3 GB
Runtime1.2 GB
Headroom6.4 GB

Performance by workload

WorkloadGradeFitDecodeTTFTContext
Agentic CodingCRuns well39.4 tok/s7138 ms8K
ChatCRuns well39.4 tok/s2677 ms8K
CodingCRuns well39.4 tok/s4908 ms8K
RAGCRuns well39.4 tok/s8923 ms8K
ReasoningCRuns well39.4 tok/s5800 ms8K

Quantization options

How Falcon 40B Instruct (40B params) fits at each quantization level on AMD Instinct MI210 64GB (64.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
15.6 GB
LowD34
Q3_K_S
3
19.6 GB
LowD35
NVFP4
4
22.4 GB
MediumD36
Q4_K_M
4
24.4 GB
MediumD37
Q5_K_M
5
28.8 GB
HighD38
Q6_K
6
32.8 GB
HighD40
Q8_0Best for your GPU
8
42.8 GB
Very HighC43
F16
16
82.0 GB
MaximumF0

Get started

Ollama
ollama run falcon-40b-instruct
HuggingFace
huggingface-cli download falcon-40b-instruct

Upgrade options

Hardware that runs Falcon 40B Instruct well

NVIDIANVIDIA H100 80GBBudget pick
C99.7 tok/s decode

~$40,000 MSRP

NVIDIANVIDIA H800 80GBBiggest leap
C86.1 tok/s decode

 

See all results for AMD Instinct MI210 64GBSee all hardware for Falcon 40B Instruct