Question 1

Can AMD Instinct MI250 128GB run Qwen3-Coder-Next?

Accepted Answer

Yes, AMD Instinct MI250 128GB can run Qwen3-Coder-Next with a C grade (Runs well). Expected decode speed: 143.1 tok/s.

Question 2

How much VRAM does Qwen3-Coder-Next need?

Accepted Answer

Qwen3-Coder-Next (80B parameters) requires approximately 63.6 GB of memory with Q4_K_M quantization.

Question 3

What is the best quantization for Qwen3-Coder-Next?

Accepted Answer

The recommended quantization for Qwen3-Coder-Next is Q4_K_M, which balances quality and memory efficiency.

Workload	Grade	Fit	Decode	TTFT	Context
Agentic Coding	C	Runs well	135.1 tok/s	2084 ms	64K
Chat	C	Runs well	135.1 tok/s	782 ms	16K
Coding	C	Runs well	143.1 tok/s	1353 ms	32K
RAG	C	Runs well	135.1 tok/s	2605 ms	64K
Reasoning	C	Runs well	135.1 tok/s	1693 ms	32K

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	31.2 GB	Low	D35
Q3_K_S	3	39.2 GB	Low	D36
NVFP4	4

Can AMD Instinct MI250 128GB run Qwen3-Coder-Next?

Memory breakdown