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All estimates are approximations based on mathematical models and public specifications. Actual performance may vary. Do not make purchasing decisions based solely on these estimates.

Data sourced from Hugging Face, Ollama, and official model documentation. Model names and logos are trademarks of their respective owners.

© 2026 Will It Run AI — Fase Consulting Ibiza, S.L. (NIF: B57969656)

Home/Qwen 2.5 72B/on NVIDIA L40 48GB

Can it run?

Can NVIDIA L40 48GB run Qwen 2.5 72B?

FWon't run

Too heavy

Using Q4_K_M in Ollama

Capabilities:

Fit status

Too heavy

Decode

15.3 tok/s

TTFT

12617 ms

Safe context

13K

Memory

61.2 GB / 48.0 GB

Memory breakdown

Weights43.9 GB
KV Cache11.3 GB
Runtime1.2 GB
Headroom4.8 GB

Performance by workload

WorkloadGradeFitDecodeTTFTContext
Agentic CodingFToo heavy15.3 tok/s18352 ms21K
ChatDVery compromised (needs ~6 GB host RAM)13.6 tok/s7780 ms7K
CodingFToo heavy15.3 tok/s12617 ms13K
RAGFToo heavy15.3 tok/s22940 ms21K
ReasoningFToo heavy15.3 tok/s14911 ms13K

Quantization options

How Qwen 2.5 72B (72B params) fits at each quantization level on NVIDIA L40 48GB (48.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
28.1 GB
LowC42
Q3_K_SBest for your GPU
3
35.3 GB
LowC45
NVFP4
4
40.3 GB
MediumC45
Q4_K_M
4
43.9 GB
MediumC45
Q5_K_M
5
51.8 GB
HighF0
Q6_K
6
59.0 GB
HighF0
Q8_0
8
77.0 GB
Very HighF0
F16
16
147.6 GB
MaximumF0

Upgrade options

Hardware that runs Qwen 2.5 72B well

AppleMacBook Pro M3 Max 128GBBudget pick
C5.5 tok/s decode

~$2,499 MSRP

AppleMacBook Pro M4 Max 96GBBest value
C7.8 tok/s decode

~$2,499 MSRP

NVIDIANVIDIA GH200 96GBBiggest leap
B73.8 tok/s decode

 

NVIDIANVIDIA H20 96GBNVIDIA upgrade
B73.8 tok/s decode

 

See all results for NVIDIA L40 48GBSee all hardware for Qwen 2.5 72B