Question 1

Can AMD Instinct MI350X 288GB run Pixtral Large 124B?

Accepted Answer

Yes, AMD Instinct MI350X 288GB can run Pixtral Large 124B with a C grade (Runs well). Expected decode speed: 76.2 tok/s.

Question 2

How much VRAM does Pixtral Large 124B need?

Accepted Answer

Pixtral Large 124B (124B parameters) requires approximately 126.2 GB of memory with Q4_K_M quantization.

Question 3

What is the best quantization for Pixtral Large 124B?

Accepted Answer

The recommended quantization for Pixtral Large 124B is Q4_K_M, which balances quality and memory efficiency.

Workload	Grade	Fit	Decode	TTFT	Context
Agentic Coding	C	Runs well	77.2 tok/s	3647 ms	63K
Chat	C	Runs well	77.2 tok/s	1368 ms	20K
Coding	C	Runs well	76.2 tok/s	3001 ms	37K
RAG	C	Runs well	77.2 tok/s	4559 ms	63K
Reasoning	C	Runs well	77.2 tok/s	2963 ms	37K

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	48.4 GB	Low	D33
Q3_K_S	3	60.8 GB	Low	D34
NVFP4	4

Can AMD Instinct MI350X 288GB run Pixtral Large 124B?

Memory breakdown