Question 1

Can RTX 5080 Laptop 16GB run Mistral Nemo 12B?

Accepted Answer

Yes, RTX 5080 Laptop 16GB can run Mistral Nemo 12B with a B grade (Runs well). Expected decode speed: 75.5 tok/s.

Question 2

How much VRAM does Mistral Nemo 12B need?

Accepted Answer

Mistral Nemo 12B (12B parameters) requires approximately 12.0 GB of memory with Q4_K_M quantization.

Question 3

What is the best quantization for Mistral Nemo 12B?

Accepted Answer

The recommended quantization for Mistral Nemo 12B is Q4_K_M, which balances quality and memory efficiency.

Workload	Grade	Fit	Decode	TTFT	Context
Agentic Coding	C	Tight fit	88.1 tok/s	3195 ms	37K
Chat	B	Runs well	88.1 tok/s	1198 ms	12K
Coding	B	Runs well	75.5 tok/s	2563 ms	21K
RAG	C	Tight fit	88.1 tok/s	3994 ms	37K
Reasoning	B	Runs well	88.1 tok/s	2596 ms	21K

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	4.7 GB	Low	D35
Q3_K_S	3	5.9 GB	Low	D37
NVFP4	4

Can RTX 5080 Laptop 16GB run Mistral Nemo 12B?

Memory breakdown