Question 1

Can Radeon PRO W7900 DS 48GB run Mistral Large 3?

Accepted Answer

No, Mistral Large 3 requires more memory than Radeon PRO W7900 DS 48GB provides.

Question 2

How much VRAM does Mistral Large 3 need?

Accepted Answer

Mistral Large 3 (675B parameters) requires approximately 425.4 GB of memory with Q4_K_M quantization.

Question 3

What is the best quantization for Mistral Large 3?

Accepted Answer

The recommended quantization for Mistral Large 3 is Q4_K_M, which balances quality and memory efficiency.

Workload	Grade	Fit	Decode	TTFT	Context
Agentic Coding	F	Too heavy	4.3 tok/s	64974 ms	4K
Chat	F	Too heavy	4.3 tok/s	24365 ms	4K
Coding	F	Too heavy	4.3 tok/s	44669 ms	4K
RAG	F	Too heavy	4.3 tok/s	81217 ms	4K
Reasoning	F	Too heavy	4.3 tok/s	52791 ms	4K

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	263.3 GB	Low	F0
Q3_K_S	3	330.8 GB	Low	F0
NVFP4	4

Can Radeon PRO W7900 DS 48GB run Mistral Large 3?

Memory breakdown