Question 1

Can AMD Instinct MI250X 128GB run Llama 4 Maverick 17B 128E?

Accepted Answer

No, Llama 4 Maverick 17B 128E requires more memory than AMD Instinct MI250X 128GB provides.

Question 2

How much VRAM does Llama 4 Maverick 17B 128E need?

Accepted Answer

Llama 4 Maverick 17B 128E (400B parameters) requires approximately 261.9 GB of memory with Q4_K_M quantization.

Question 3

What is the best quantization for Llama 4 Maverick 17B 128E?

Accepted Answer

The recommended quantization for Llama 4 Maverick 17B 128E is Q4_K_M, which balances quality and memory efficiency.

Workload	Grade	Fit	Decode	TTFT	Context
Agentic Coding	F	Too heavy	28.3 tok/s	9961 ms	15K
Chat	F	Too heavy	28.3 tok/s	3735 ms	4K
Coding	F	Too heavy	28.3 tok/s	6848 ms	8K
RAG	F	Too heavy	28.3 tok/s	12451 ms	15K
Reasoning	F	Too heavy	28.3 tok/s	8093 ms	8K

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	156.0 GB	Low	F0
Q3_K_S	3	196.0 GB	Low	F0
NVFP4	4

Can AMD Instinct MI250X 128GB run Llama 4 Maverick 17B 128E?

Memory breakdown