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All estimates are approximations based on mathematical models and public specifications. Actual performance may vary. Do not make purchasing decisions based solely on these estimates.

Data sourced from Hugging Face, Ollama, and official model documentation. Model names and logos are trademarks of their respective owners.

© 2026 Will It Run AI — Fase Consulting Ibiza, S.L. (NIF: B57969656)

Home/Kimi K2.5/on AMD Instinct MI250X 128GB

Can it run?

Can AMD Instinct MI250X 128GB run Kimi K2.5?

FWon't run

Too heavy

Using Q4_K_M in vLLM

Capabilities:

Fit status

Too heavy

Decode

12.6 tok/s

TTFT

15405 ms

Safe context

4K

Memory

630.2 GB / 128.0 GB

Memory breakdown

Weights610.0 GB
KV Cache5.0 GB
Runtime2.4 GB
Headroom12.8 GB

Performance by workload

WorkloadGradeFitDecodeTTFTContext
Agentic CodingFToo heavy12.6 tok/s22408 ms6K
ChatFToo heavy12.6 tok/s8403 ms4K
CodingFToo heavy12.6 tok/s15405 ms4K
RAGFToo heavy12.6 tok/s28010 ms6K
ReasoningFToo heavy12.6 tok/s18206 ms4K

Quantization options

How Kimi K2.5 (1000B params) fits at each quantization level on AMD Instinct MI250X 128GB (128.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
390.0 GB
LowF0
Q3_K_S
3
490.0 GB
LowF0
NVFP4
4
560.0 GB
MediumF0
Q4_K_M
4
610.0 GB
MediumF0
Q5_K_M
5
720.0 GB
HighF0
Q6_K
6
820.0 GB
HighF0
Q8_0
8
1070.0 GB
Very HighF0
F16
16
2050.0 GB
MaximumF0
See all results for AMD Instinct MI250X 128GBSee all hardware for Kimi K2.5