Question 1

Can RTX PRO 5000 Blackwell 48GB run Qwen3.5 27B?

Accepted Answer

Yes, RTX PRO 5000 Blackwell 48GB can run Qwen3.5 27B with a C grade (Runs well). Expected decode speed: 58.8 tok/s.

Question 2

How much VRAM does Qwen3.5 27B need?

Accepted Answer

Qwen3.5 27B (27B parameters) requires approximately 26.7 GB of memory with Q4_K_M quantization.

Question 3

What is the best quantization for Qwen3.5 27B?

Accepted Answer

The recommended quantization for Qwen3.5 27B is Q4_K_M, which balances quality and memory efficiency.

Workload	Grade	Fit	Decode	TTFT	Context
Agentic Coding	B	Runs well	68.5 tok/s	4108 ms	50K
Chat	C	Runs well	68.5 tok/s	1541 ms	16K
Coding	C	Runs well	58.8 tok/s	3295 ms	29K
RAG	B	Runs well	68.5 tok/s	5135 ms	50K
Reasoning	C	Runs well	68.5 tok/s	3338 ms	29K

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	10.5 GB	Low	D34
Q3_K_S	3	13.2 GB	Low	D35
NVFP4	4

Can RTX PRO 5000 Blackwell 48GB run Qwen3.5 27B?

Memory breakdown