How much VRAM does Qwen3.5 27B need?

Qwen3.5 27B (27B parameters) requires approximately 26.7 GB of memory with Q4_K_M quantization.

What is the best quantization for Qwen3.5 27B?

The recommended quantization for Qwen3.5 27B is Q4_K_M, which balances quality and memory efficiency.

Can it run?

Yes, Radeon Pro W7900 48GB can run Qwen3.5 27B with a C grade (Runs well). Expected decode speed: 31.0 tok/s.

CUsable

Runs well

Using Q4_K_M in Ollama

Capabilities:

Fit status

Runs well

Decode

31.0 tok/s

TTFT

6255 ms

Safe context

29K

Memory

26.7 GB / 48.0 GB

Weights16.5 GB

KV Cache4.2 GB

Runtime1.2 GB

Headroom4.8 GB

Workload	Grade	Fit	Decode	TTFT	Context
Agentic Coding	C	Runs well	31.0 tok/s	9098 ms	50K
Chat	C	Runs well	31.0 tok/s	3412 ms	16K
Coding	C	Runs well	31.0 tok/s	6255 ms	29K
RAG	C	Runs well	31.0 tok/s	11373 ms	50K
Reasoning	C	Runs well	31.0 tok/s	7392 ms	29K

How Qwen3.5 27B (27B params) fits at each quantization level on Radeon Pro W7900 48GB (48.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	10.5 GB	Low	D34
Q3_K_S	3	13.2 GB	Low	D35
NVFP4	4

HuggingFace

huggingface-cli download hf-unsloth--qwen3-5-27b-gguf

Upgrade options

AMD Instinct MI210 64GBBudget pick

C67.6 tok/s decode

~$10,000 MSRP