How much VRAM does Qwen3.5 27B need?

Qwen3.5 27B (27B parameters) requires approximately 25.1 GB of memory with Q4_K_M quantization.

What is the best quantization for Qwen3.5 27B?

The recommended quantization for Qwen3.5 27B is Q4_K_M, which balances quality and memory efficiency.

Can it run?

Yes, AMD Instinct MI100 32GB can run Qwen3.5 27B with a B grade (Runs well). Expected decode speed: 48.5 tok/s.

BGood

Runs well

Using Q4_K_M in Ollama

Capabilities:

Fit status

Runs well

Decode

48.5 tok/s

TTFT

3995 ms

Safe context

20K

Memory

25.1 GB / 32.0 GB

Weights16.5 GB

KV Cache4.2 GB

Runtime1.2 GB

Headroom3.2 GB

Workload	Grade	Fit	Decode	TTFT	Context
Agentic Coding	C	Tight fit	48.5 tok/s	5811 ms	35K
Chat	B	Runs well	48.5 tok/s	2179 ms	11K
Coding	B	Runs well	48.5 tok/s	3995 ms	20K
RAG	C	Tight fit	48.5 tok/s	7263 ms	35K
Reasoning	B	Runs well	48.5 tok/s	4721 ms	20K

How Qwen3.5 27B (27B params) fits at each quantization level on AMD Instinct MI100 32GB (32.0 GB usable).

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	10.5 GB	Low	D37
Q3_K_S	3	13.2 GB	Low	D38
NVFP4	4

HuggingFace

huggingface-cli download hf-unsloth--qwen3-5-27b-gguf

Upgrade options

NVIDIA A100 40GBBudget pick

B79.3 tok/s decode

~$10,000 MSRP