Question 1

Can AMD Instinct MI100 32GB run Mistral Small 3.2 24B Instruct 2506?

Accepted Answer

Yes, AMD Instinct MI100 32GB can run Mistral Small 3.2 24B Instruct 2506 with a B grade (Runs well). Expected decode speed: 60.4 tok/s.

Question 2

How much VRAM does Mistral Small 3.2 24B Instruct 2506 need?

Accepted Answer

Mistral Small 3.2 24B Instruct 2506 (24B parameters) requires approximately 22.8 GB of memory with Q4_K_M quantization.

Question 3

What is the best quantization for Mistral Small 3.2 24B Instruct 2506?

Accepted Answer

The recommended quantization for Mistral Small 3.2 24B Instruct 2506 is Q4_K_M, which balances quality and memory efficiency.

Workload	Grade	Fit	Decode	TTFT	Context
Agentic Coding	C	Tight fit	54.5 tok/s	5165 ms	39K
Chat	C	Runs well	54.5 tok/s	1937 ms	12K
Coding	B	Runs well	60.4 tok/s	3206 ms	22K
RAG	C	Tight fit	54.5 tok/s	6456 ms	39K
Reasoning	B	Runs well	54.5 tok/s	4196 ms	22K

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	9.4 GB	Low	D36
Q3_K_S	3	11.8 GB	Low	D37
NVFP4	4

Can AMD Instinct MI100 32GB run Mistral Small 3.2 24B Instruct 2506?

Memory breakdown