Question 1

Can AMD Instinct MI250 128GB run DeepSeek R1 0528 Qwen3 8B?

Accepted Answer

Yes, AMD Instinct MI250 128GB can run DeepSeek R1 0528 Qwen3 8B with a C grade (Runs well). Expected decode speed: 445.9 tok/s.

Question 2

How much VRAM does DeepSeek R1 0528 Qwen3 8B need?

Accepted Answer

DeepSeek R1 0528 Qwen3 8B (8B parameters) requires approximately 20.1 GB of memory with Q4_K_M quantization.

Question 3

What is the best quantization for DeepSeek R1 0528 Qwen3 8B?

Accepted Answer

The recommended quantization for DeepSeek R1 0528 Qwen3 8B is Q4_K_M, which balances quality and memory efficiency.

Workload	Grade	Fit	Decode	TTFT	Context
Agentic Coding	C	Runs well	445.9 tok/s	632 ms	192K
Chat	C	Runs well	445.9 tok/s	350 ms	52K
Coding	C	Runs well	445.9 tok/s	434 ms	102K
RAG	C	Runs well	445.9 tok/s	789 ms	192K
Reasoning	C	Runs well	445.9 tok/s	513 ms	102K

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	3.1 GB	Low	D30
Q3_K_S	3	3.9 GB	Low	D30
NVFP4	4

Can AMD Instinct MI250 128GB run DeepSeek R1 0528 Qwen3 8B?

Memory breakdown