Question 1

Can RTX PRO 5000 Blackwell 48GB run Hermes 4.3 36B?

Accepted Answer

Yes, RTX PRO 5000 Blackwell 48GB can run Hermes 4.3 36B with a C grade (Runs well). Expected decode speed: 44.1 tok/s.

Question 2

How much VRAM does Hermes 4.3 36B need?

Accepted Answer

Hermes 4.3 36B (36B parameters) requires approximately 33.6 GB of memory with Q4_K_M quantization.

Question 3

What is the best quantization for Hermes 4.3 36B?

Accepted Answer

The recommended quantization for Hermes 4.3 36B is Q4_K_M, which balances quality and memory efficiency.

Workload	Grade	Fit	Decode	TTFT	Context
Agentic Coding	C	Runs well	51.4 tok/s	5478 ms	39K
Chat	C	Runs well	51.4 tok/s	2054 ms	12K
Coding	C	Runs well	44.1 tok/s	4393 ms	23K
RAG	C	Runs well	51.4 tok/s	6847 ms	39K
Reasoning	C	Runs well	51.4 tok/s	4451 ms	23K

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	14.0 GB	Low	D35
Q3_K_S	3	17.6 GB	Low	D37
NVFP4	4

Can RTX PRO 5000 Blackwell 48GB run Hermes 4.3 36B?

Memory breakdown