Question 1

Can AMD Instinct MI250X 128GB run SmolVLM 500M Instruct?

Accepted Answer

Yes, AMD Instinct MI250X 128GB can run SmolVLM 500M Instruct with a C grade (Runs well). Expected decode speed: 2419.2 tok/s.

Question 2

How much VRAM does SmolVLM 500M Instruct need?

Accepted Answer

SmolVLM 500M Instruct (0.5B parameters) requires approximately 15.2 GB of memory with Q6_K quantization.

Question 3

What is the best quantization for SmolVLM 500M Instruct?

Accepted Answer

The recommended quantization for SmolVLM 500M Instruct is Q6_K, which balances quality and memory efficiency.

Workload	Grade	Fit	Decode	TTFT	Context
Agentic Coding	C	Runs well	2419.2 tok/s	350 ms	269K
Chat	C	Runs well	2419.2 tok/s	350 ms	67K
Coding	C	Runs well	2419.2 tok/s	350 ms	135K
RAG	C	Runs well	2419.2 tok/s	350 ms	269K
Reasoning	C	Runs well	2419.2 tok/s	350 ms	135K

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	0.2 GB	Low	D29
Q3_K_S	3	0.2 GB	Low	D29
NVFP4	4

Can AMD Instinct MI250X 128GB run SmolVLM 500M Instruct?

Memory breakdown