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All estimates are approximations based on mathematical models and public specifications. Actual performance may vary. Do not make purchasing decisions based solely on these estimates.

Data sourced from Hugging Face, Ollama, and official model documentation. Model names and logos are trademarks of their respective owners.

© 2026 Will It Run AI — Fase Consulting Ibiza, S.L. (NIF: B57969656)

Home/DeepSeek V2.5 236B/on AMD Instinct MI350X 288GB

Can it run?

Can AMD Instinct MI350X 288GB run DeepSeek V2.5 236B?

BGood

Runs well

Using Q4_K_M in vLLM

Capabilities:

Fit status

Runs well

Decode

109.3 tok/s

TTFT

1771 ms

Safe context

26K

Memory

178.4 GB / 288.0 GB

Memory breakdown

Weights144.0 GB
KV Cache3.3 GB
Runtime2.4 GB
Headroom28.8 GB

Performance by workload

WorkloadGradeFitDecodeTTFTContext
Agentic CodingBRuns well109.3 tok/s2577 ms51K
ChatBRuns well109.3 tok/s966 ms13K
CodingBRuns well109.3 tok/s1771 ms26K
RAGBRuns well109.3 tok/s3221 ms51K
ReasoningBRuns well109.3 tok/s2094 ms26K

Quantization options

How DeepSeek V2.5 236B (236B params) fits at each quantization level on AMD Instinct MI350X 288GB (288.0 GB usable).

QuantBitsVRAMQualityFit
Q2_K
2
92.0 GB
LowD36
Q3_K_S
3
115.6 GB
LowD38
NVFP4
4
132.2 GB
MediumD39
Q4_K_M
4
144.0 GB
MediumD40
Q5_K_M
5
169.9 GB
HighC42
Q6_KBest for your GPU
6
193.5 GB
HighC44
Q8_0
8
252.5 GB
Very HighC44
F16
16
483.8 GB
MaximumF0

Get started

Ollama
ollama run deepseek-v2.5-236b
HuggingFace
huggingface-cli download deepseek-v2.5-236b
See all results for AMD Instinct MI350X 288GBSee all hardware for DeepSeek V2.5 236B