Question 1

Can AMD Instinct MI350X 288GB run Command R+ 104B?

Accepted Answer

Yes, AMD Instinct MI350X 288GB can run Command R+ 104B with a C grade (Runs well). Expected decode speed: 90.8 tok/s.

Question 2

How much VRAM does Command R+ 104B need?

Accepted Answer

Command R+ 104B (104B parameters) requires approximately 110.9 GB of memory with Q4_K_M quantization.

Question 3

What is the best quantization for Command R+ 104B?

Accepted Answer

The recommended quantization for Command R+ 104B is Q4_K_M, which balances quality and memory efficiency.

Workload	Grade	Fit	Decode	TTFT	Context
Agentic Coding	C	Runs well	92.1 tok/s	3059 ms	72K
Chat	C	Runs well	92.1 tok/s	1147 ms	22K
Coding	C	Runs well	90.8 tok/s	2517 ms	42K
RAG	C	Runs well	92.1 tok/s	3824 ms	72K
Reasoning	C	Runs well	92.1 tok/s	2485 ms	42K

Quant	Bits	VRAM	Quality	Fit
Q2_K	2	40.6 GB	Low	D32
Q3_K_S	3	51.0 GB	Low	D33
NVFP4	4

Can AMD Instinct MI350X 288GB run Command R+ 104B?

Memory breakdown